* Malaria Cell Atlas Logo

Malaria Cell Atlas

Data sets

Explore all data sets below

SpeciesLibrary typeCells/stages profiledDescription and links
P. berghei 10x 3' v3 & SS2 Asexual and sexual intraerythrocytic stages

P. berghei 10x & SS2 set2

This dataset profiles ~6k cells collected over a time course of gametocyte development

Regulators of male and female sexual development critical for transmission of a malaria parasite

Andrew J C Russell et al bioRxiv 2021;2021.08.04.455056 10.1101/2021.08.04.455056

P. berghei Smart-Seq2  Asexual and sexual intraerythrocytic stages, mosquito stages  

P. berghei SS2 set1

This dataset profiles ~1800 cells examining full life cycle stages 

The Malaria Cell Atlas: Single parasite transcriptomes across the complete life cycle.

Howick VM et al Science 2019;365;6455 10.1126/science.aaw2619

P. berghei 10x 3'v3 Asexual intraerythrocytic stages

P. berghei 10x set1

This dataset profiles ~5k cells across the asexual stages

The Malaria Cell Atlas: Single parasite transcriptomes across the complete life cycle.

Howick VM et al Science 2019;365;6455 10.1126/science.aaw2619

P. falciparum 10x 3' v3 Asexual and sexual intraerythrocytic stages

P. falciparum 10x set3

This dataset profiles ~30k cells collected over a time course of gametocyte development, from asexual blood stages through to stage V gametocytes

Manuscript in preparation

P. falciparum 10x 3' v2 Asexual intraerythrocytic stages  

P. falciparum 10x Competition Growth

This dataset profiles ~8k cells across the asexual stages of 6 strains, grown together in competition and individually 

Souporcell: robust clustering of single-cell RNA-seq data by genotype without reference genotypes.

Heaton H et al Nature Methods 2020;17;6;615-620 10.1038/s41592-020-0820-1

P. falciparum 10x 3' v2 & v3 Asexual and sexual intraerythrocytic stages

P. falciparum 10x set2

This dataset profiles ~30k cells collected over a time course of gametocyte development, from asexual blood stages through to stage V gametocytes

Manuscript in preparation

P. falciparum Smart-Seq2 Asexual and sexual intraerythrocytic stages, mosquito stages  

P. falciparum SS2 set1

This dataset profiles ~2k cells across the full life stages

Single-cell RNA-seq reveals hidden transcriptional variation in malaria parasites.

Reid AJ et al eLife 2018;7 10.7554/eLife.33105

A single-cell atlas of Plasmodium falciparum transmission through the mosquito.

Real E et al Nature Communications 2021;12;1;3196 10.1038/s41467-021-23434-z

P. falciparum 10x 3' v2 Asexual intraerythrocytic stages  

P. falciparum 10x set1

This dataset profiles ~6k cells across the asexual stages

The Malaria Cell Atlas: Single parasite transcriptomes across the complete life cycle.

Howick VM et al Science 2019;365;6455 10.1126/science.aaw2619

P. knowlesi 10x 3' v2 Asexual intraerythrocytic stages  

P. knowlesi 10x set1

This dataset profiles ~6k cells across the asexual stages 

The Malaria Cell Atlas: Single parasite transcriptomes across the complete life cycle.

Howick VM et al Science 2019;365;6455 10.1126/science.aaw2619

P. malariae 10x 3' v3 Circulating intraerythrocytic stages  

P. malariae Chromium 10x set1

This dataset profiles ~300 cells collected from an symptomatic malaria patient, covering the circulating asexual and sexual blood stages

P. ovale 10x 3' v3 Circulating intraerythrocytic stages

P. ovale Chromium 10x set1

This dataset profiles ~2500 cells collected from a symptomatic malaria patient, covering the circulating asexual and sexual blood stages

Manuscript in preparation